Publications

REACH Publications

Publications resulting from REACH funding include:

J. Zhou, P. F. Damasceno, R. Chachad, J. R. Cheung, A. Ballatori, J.C. Lotz, A.A. Lazar, Th.M. Link, A.J. Fields, R. Krug. Automatic Vertebral Body Segmentation Based on Deep Learning of Dixon Images for Bone Marrow Fat Fraction Quantification. https://doi.org/10.3389/fendo.2020.00612

Stefan Dudli, Alexander Ballatori, Anne-Christine Bay-Jensen, Zachary L McCormick, Conor W O'Neill, Sibel Demir-Deviren, Roland Krug, Irina Heggli, Astrid Juengel, Jaro Karppinen, Florian Brunner, Mazda Farshad, Oliver Distler, Jeffrey C Lotz, Aaron J Fields. Serum biomarkers for connective tissue and basement membrane remodeling are associated with vertebral endplate bone marrow lesions as seen on MRI (Modic Changes). Int J Mol Sci.2020 May 27;21(11):3791. doi: 10.3390/ijms21113791.

Wang L, Han M, Wong J, Zheng P, Lazar AA, Krug R, Fields AJ. Evaluation of human cartilage endplate composition using MRI: spatial variation, association with adjacent disc degeneration, and in vivo repeatability. J Orthop Res. 2020 Jun 27. PMID: 32592504.

REACH faculty have broad expertise in their specific areas of research focus. Below we have highlighted some of their published work, as well as articles that may be of interested to the lower back pain community at large. 

Bailey JF, Fields AJ, Ballatori A, et al. The Relationship Between Endplate Pathology and Patient-reported Symptoms for Chronic Low Back Pain Depends on Lumbar Paraspinal Muscle Quality. Spine (Phila Pa 1976). 2019;44(14):1010‐1017. doi:10.1097/BRS.0000000000003035

 

Chan AK, Bisson EF, Bydon M, et al. A comparison of minimally invasive transforaminal lumbar interbody fusion and decompression alone for degenerative lumbar spondylolisthesis. Neurosurg Focus. 2019;46(5):E13. doi:10.3171/2019.2.FOCUS18722

Chan AK, Bisson EF, Bydon M, et al. Laminectomy alone versus fusion for grade 1 lumbar spondylolisthesis in 426 patients from the prospective Quality Outcomes Database. J Neurosurg Spine. 2018;30(2):234–241. doi:10.3171/2018.8.SPINE17913

Ghogawala Z, Shaffrey CI, Asher AL, Heary RF, Logvinenko T, Malhotra NR, Dante SJ, Hurlbert RJ, Douglas AF, Magge SN, Mummaneni PV, Cheng JS, Smith JS, Kaiser MG, Abbed KM, Sciubba DM, Resnick DK. The efficacy of lumbar discectomy and single-level fusion for spondylolisthesis: results from the NeuroPoint-SD registry: clinical article. J Neurosurg Spine. 2013 Nov;19(5):555-63. doi: 10.3171/2013.7.SPINE1362. Epub 2013 Sep 6.

Lotz JC, Fields AJ, Liebenberg EC. The role of the vertebral end plate in low back pain. Global Spine J. 2013;3(3):153‐164. doi:10.1055/s-0033-1347298

Krug R, Joseph GB, Han M, Fields A, Cheung J, Mundada M, Bailey J, Rochette A, Ballatori A, McCulloch CE, McCormick Z, O'Neill C, Link TM, Lotz J. Associations between vertebral body fat fraction and intervertebral disc biochemical composition as assessed by quantitative MRI. J Magn Reson Imaging. 2019.

Mummaneni PV, Whitmore RG, Curran JN, Ziewacz JE, Wadhwa R, Shaffrey CI, Asher AL, Heary RF, Cheng JS, Hurlbert RJ, Douglas AF, Smith JS, Malhotra NR, Dante SJ, Magge SN, Kaiser MG, Abbed KM, Resnick DK, Ghogawala Z. Cost-effectiveness of lumbar discectomy and single-level fusion for spondylolisthesis: experience with the NeuroPoint-SD registry. Neurosurg Focus. 2014 Jun;36(6):E3. doi: 10.3171/2014.3.FOCUS1450.

 

Than KD, Curran JN, Resnick DK, Shaffrey CI, Ghogawala Z, Mummaneni PV. How to predict return to work after lumbar discectomy: answers from the NeuroPoint-SD registry. J Neurosurg Spine. 2016 Aug;25(2):181-6. doi: 10.3171/2015.10.SPINE15455. Epub 2016 Mar 18. PMID: 26989977 Clinical Trial.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

© 2020 Core Center for Patient-centric, Mechanistic Phenotyping in Chronic Low Back Pain